Ana-Maria Catana @AnaPath10
Specialist Assistant at Comprehensive Cancer Centers (CLCCs) France Joined June 2022-
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Ana-Maria Catana retweeted
Mastocytosis (seen here) is often sought by naive colleagues and seldom seen. Mod Pathol offers a great review: Panarelli NC, Hornick JL, Yantiss RK. What Is the Value of Counting Mast Cells in Gastrointestinal Mucosal Biopsies? Mod Pathol. 2023 Feb;36(2):100005. PMID: 36853780.
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Ana-Maria Catana retweeted
Our Gynecologic Pathology cases @UMiamiPathology are fascinating! Here’s a striking example of pilomatrix-like high-grade endometrial carcinoma (PiMHEC), a recently described entity mostly driven by CTNNB1 mutations. Look for solid basaloid growth with conspicuous central tumor cell necrosis, and pilomatrix-like keratinization with the hallmark ghost cells. This case also had a focal conventional FIGO grade 1 endometrioid component. IHC shows diffuse nuclear β-catenin with loss of PAX8 and ER in the pilomatrix-like component. These tumors are believed to behave aggressively.
Ana-Maria Catana retweeted
1/ Necrosis = cell death (unlike apoptosis, it does not occur naturally and is not programmed) This short #Tweetorial shows you some of the histologic flavors of necrosis. The stain in each of these pics is hematoxylin-eosin (H&E) #pathology #pulmpath #pathtweetorial
Ana-Maria Catana retweeted
Ana-Maria Catana retweeted
Fact or artifact? 😰 Poor Fixation 🔬 Underfixation can make perfectly benign TDLUs look discohesive and atypical, mimicking atypical lobular hyperplasia (ALH). #PathX #PathTwitter #breasthpath
Ana-Maria Catana retweeted
Not all that has ink is a true margin. 1. Make sure the ink is not in a cleft between fat lobules 2. Make sure you have a full cross-section of the tissue in the block. Tissue disruptions with ink are to be considered artifactual until proven otherwise 3. Check the diagram that shows where the section was taken from 4. If in doubt, walk over to the histology and lab and ask for the paraffin block. Looking at the entirety of the tissue within the block will give you information you cannot easily glean from the two-dimensional slide #breastpath
Ana-Maria Catana retweeted
40 year old with a skin mass above sternum, R/O lipoma. Herniated lung??? probably not :)
@fouad_boulos Lactating adenoma :o
Ana-Maria Catana retweeted
New thread: is it consistent with sarcoidosis? 1/ Yes!
Asteroid body in a foreign body mutinucleated giant cell. This is an axillary LB biopsy from a patient w/ breast implant #pathresidents #pathX
Ana-Maria Catana retweeted
An example of crystal storing histiocytosis; the patient needs to be evaluated for a plasma cell disorder or other lambda-restricted B cell neoplasm. Arnold CA, et al. Am J Surg Pathol. 2018 Oct;42(10):1317-1324. PMID: 29878935.
Ana-Maria Catana retweeted
“Appendiceal mucinous neoplasm" is being introduced in the WHO 6th ed (beta version) to define a "circumferential proliferation of neoplastic mucinous epithelial cells confined to the mucosa, with an intact muscularis mucosae, originating in the appendix." Wouldn't exclude SSL w/ dysplasia, but again, it doesn't really matter (and MLH1 loss wouldn't help in the appendix like it does in the rest of the colon).
@MateenH79781868 @pepeheffernan @malakbehnas @FionaMacPath @AnupamaArya12 @DrGeeONE I’d call it appendiceal mucinous adenoma, on these images. Of course, mucinous lesions should be entirely submitted, and if there’s even focal architectural disturbance,I’d call it LAMN. Appendectomy is curative either way. What matters here is the absence of peritoneal disease.
Ana-Maria Catana retweeted
If you submitted all the appendix and you don't see epithelium, just mucin in the lumen, sign it as: -Dilated appendix with mucin Comment: The differential includes LAMN or reactive processes Dr. Umetsu #CAP23 #everydayGI #GIpath #PathX #PathTwitter #pathology #pathologists
Ana-Maria Catana retweeted
Appendix Postinflammatory mucosal hyperplasia -Associated with acute/interval appendicitis -Epithelium looks hyperplastic/serrated near surface -This is not LAMN ⚠️ #surgpath #pathology #PathTwitter #GIpath CAP today digital.olivesoftware.com/olive/odn/capt… Thanks for sharing @Voltaggiol 🌟
Ana-Maria Catana retweeted
Challenges of staging appendiceal mucinous neoplasms Mucin outside the appendix in a LAMN case, is it pT4 or not? -Acellular mucin without inflammatory reaction, mesothelial hyperplasia, or neovascularization is presumed to be a result of carryover during handling or gross examination, and should not be designated as pT4a (Pic A) - Organizing acellular mucin with neovascularization on the serosal surface is categorized as pT4a (Pic B) Umetsu et al doi.org/10.1016/j.hump…
Ana-Maria Catana retweeted
When large nests of tumor surround a completely normal duct, they are much more likely to be invasive cancer or lymphovascular invasion than DCIS. A useful pattern to remember on a biopsy #breastpath
Ana-Maria Catana retweeted
#GUpath prostate bx: Gleason score 3+4, with pattern 4 comprised of glomerulation and poorly formed glands
Ana-Maria Catana retweeted
Pagetoid Spread of ALH ⛏️👷♂️🔬 Dyshesive atypical lobular cells undermining and spreading along the undersurface of the ductal epithelium in a pagetoid pattern—subtle and may mimic myoepthelial cell hyperplasia. #PathX #PathTwitter #breastpath
Jerad Gardner, MD @JMGardnerMD
51K Followers 15K Following Dermpath/Sarcoma Pathologist & Residency Program Director @GeisingerPath. Co-founder @Kiko4docs. DepEd @ArchivesPath. Author: Survival Guide to Dermatopathology
Tristan Rutland MBBS ... @TristanRutland7
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Tristan Rutland MBBS ... @TristanRutland7
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Janira Navarro @Janiranavarro
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Ankur Sangoi @slusagar
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Syed Z. Ali @sza_jhcyto
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Pathology @mvmd0908
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Dr. Shalini Radhakris... @shalinirkr21
471 Followers 231 Following She/Her | ICP-PDCC Fellow: Gastrointestinal & Hepatic Pathology, VPS Lakeshore, Kochi | PGY-3+1
Dharam Ramnani, MD @DharamRamnani
353 Followers 143 Following pathologist, founder of WebPathology (@WebPathology), interested in astronomy, quantum physics, single malts, sufi music, mughal architecture & vinyl
Dongling Wu MD @Emmadon53528883
736 Followers 1K Following GU trained @NYUGSOM_Path, Breast trained @BIDMCpath. Current Surg path fellow @MSKpathology. Future breast and GU pathologist @BIDMCpath. Matthew 6:33
Adelina Baltan @AdelinaBaltan
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João Marçal Medeiro... @JooMMdeSousa1
54 Followers 291 Following Pathology Resident at Federal University of Juiz de Fora (Minas Gerais - Brazil) 🔬🇧🇷
Zemplén Pataki, MD, ... @ZemplenPataki
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Muath Alyahya @muathalyahya5
188 Followers 735 Following Dermatopathologist | Gastrointestinal & Pancreas Pathologist 🔬🇸🇦 🇨🇦
Yusef Almarzooq @yusefalmarzooq
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Masako Le-Maciukiewic... @MasakoLeMD
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860 Followers 59 Following
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aung phyo @pathphyo
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801 Followers 798 Following Pathologist, Mom,Thamizhian( yes I’m proud of that)...In perpetual awe of the magic of what colours and patterns can bring about..You might like
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