ENIGMA-Addiction Consortium @AddictionEnigma
The ENIGMA-Addiction working group analyzes data relevant to addiction phenotypes including case-control comparisons across a variety of substances. enigmaaddictionconsortium.com Burlington, Vermont Joined February 2020-
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The #genetics that contribute to quantity of #alcohol consumed only partially overlaps with the genetics that contribute to alcohol use disorder (#addiction). Similar for #cannabis. @PGCgenetics Substance Use Disorder group.
A #GWAS of a common #genetic vulnerability factor that underlies several substance use disorders (#addictions) identified 19 independent risk loci, many related to #dopaminergic signaling & regulation (@AlexanderHatoum, Nature Mental Health, in press; bit.ly/3VzzFtd) 2/2
Substance use disorders (SUDs, #addiction) are defined by problems caused by misuse of a drug, i.e. #alcohol use disorder by problems caused by misuse of alcohol. There is a lot of comorbidity among SUDs. Current #genetic findings reviewed: bit.ly/3wlTiLN (1/10)
A GWAS of the factors showed some #genes associated with consumption and others with problems. bit.ly/3NcfsWr (4/4)
Job alert!! 📢🚨 We are looking for postdoc to join us. Candidate must have completed doctorate training in a neuroscience-related discipline. Experience with MRI and genetics desirable. More info and contact details in the link below 👇 enigmaaddictionconsortium.com/forum/__all/po…
for those who have missed it here's the latest ENIGMA-Addiction video call hosted on March 23rd – special focus on polygenic risk scores 🧬 and fMRI🧠 projects! #Addiction #neurotwitter #genetics @enigmabrains enigmaaddictionconsortium.com/copy-of-video-…
You are invited to join @ENIGMA_ACRI consortium to do mega analysis for biomarker development with fMRI drug cue reactivity with over 2000 subjects/imaging so far! @AddictionEnigma @enigmabrains @AZilverstand More details in the video: youtu.be/IlCPPe-Ertg
Our latest contribution is now available! 👏📢 Alcohol dependence in young adults and problematic drinking in adolescents is related to differences in brain structural covariance patterns (1/5) #NeuroTwitter #neuroscience #MRI #addiction onlinelibrary.wiley.com/doi/10.1111/ad…
Our #ENIGMA #Addiction #Cue_Reactivity Initiative (ENIGMA-ACRI) consensus paper, led by @EkhtiariHamed and @AZilverstand, is OUT in Nature Protocols! @NatureProtocols @nresearchnews doi.org/10.1038/s41596… Congratulations to @enigmabrains, @AddictionEnigma, and the 60 authors!
And... IT'S A WRAP! ENIGMA's 2021 Year In Review, and what a year! Take a video tour of ENIGMA's global neuroscience projects, highlighting this year's new discoveries in over 30 brain disorders, by scientists in 45+ countries! youtube.com/watch?v=JSi_Fk… PDF drive.google.com/file/d/1aQd5ew…
Our latest work led by @racharabin on gender-specific associations with cocaine use on grey matter volume is out!!! #cocaine #addiction #mri this work was part of a @OHBM special issue celebrating the @enigmabrains 10-year anniversary 🔟🎉🧠🎂 onlinelibrary.wiley.com/doi/10.1002/hb…
Human Brain Mapping Special Issue "ENIGMA: The 1st 10 Years" is OUT! 32 papers, global brain studies: onlinelibrary.wiley.com/toc/10970193/2… Kudos to 2000+ scientists making this possible, +editors @PKochunov @njahanshad @lianne_schmaal @AndersonWinkler Jess Turner Gary Egan Sophia Thomopoulos!
NEW LAB COLLABORATIVE PAPER OUT Brain structural covariance network differences in adults with alcohol dependence and heavy drinking adolescents #addiction #alcoholawareness #ImagenesQueHablan @URNeuroscience #URochesterResearch @AddictionEnigma @IsamNig onlinelibrary.wiley.com/doi/epdf/10.11…
New publication in the group!! WM differences in individuals with dependence on stimulants using data from 11 international sites. Thanks to all our members for making this work possible!! 🙏🥳
our latest work w/@AddictionEnigma is out!! 📢🧠 we explored WM differences in a multi-site sample of ~800 individuals with dependence on #cocaine, #methamphetamine and #nicotine and used #MachineLearning to derive brain-based classifications using #DTI authors.elsevier.com/a/1eAJh1LiD369…
So excited about all the fascinating projects and findings presented in the @AddictionEnigma members meeting today! 🧠Sex differences in neuroanatomy of SUD (@lorenzvnt @HBMRC_ACU), cerebellar volume & SUD (@egarzav), structural covariates of abstinence (@Leon_Fonville) and more!
Want to join us in the next one?👇👇 enigmaaddictionconsortium.com/how-to-join
better late than never – here is the latest ENIGMA-Addiction teleconference held on June '21 where we discussed polygenic risk scores and new MRI modalities available soon in the group (DTI, rs-fMRI) #addiction #neuroscience enigmaaddictionconsortium.com/copy-of-video-…
Do you have #neuroimaging or #genetic data to contribute for secondary analyses? You could become a member of @AddictionEnigma, an international working group of @enigmabrains that collects data relevant to #addiction phenotypes across substances. See flyer for further info👇
**New paper on @JAMAPsych** Cannabis use associated with accelerated cortical thinning from 14 to 19 years of age predominantly in prefrontal regions #development #brain #neuroscience Read the paper and hear the interview below: jamanetwork.com/journals/jamap…
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