that have been given about the spread of emerging or re-emerging viruses. On the other hand, the subject of the very large number of mutations, more than 50 new mutations, for Omicron or new strains of monkeypox, is rarely mentioned.
The 3 main reasons for these mutations could b - mutations that would have taken place without being detected for several months or even years, - reverse zoonoses with passages of the viruses within animal reservoirs before returning to humans
- and finally, the action of mutagenic treatments, especially for immunocompromised patients The subject of mutagens, the antiviral or antibodies treatments which, at the same time as they fight viruses, cause significant mutations in the virus is not new.
It has been thoroughly studied, especially since HIV. "Mutagenic outcome of combined antiviral drug treatment during human immunodeficiency virus type 1 replication" sciencedirect.com/science/articl…
These mutagens are part of what are called CRMs, which are mainly found in food (4.8 million tons used each year in France) - Carcinogenics that cause cancer - Mutagens that cause genetic changes - Reprotoxins that affect reproductive abilities . anses.fr/en/content/car…
For 2 and a half years, as soon as COVID emerged, antivirals or antibody-based treatments have been prescribed. Several studies have shown that these treatments have significant mutagenic effects and cause significant mutations in the virus. For Remdesivir science.org/doi/10.1126/sc…
For Monulpiravir forbes.com/sites/williamh… For Sotrovimab jamanetwork.com/journals/jama/…
This means that not only we have allowed to spread viruses all over the planet, that this has been done by causing a lowering of the immunity of populations and therefore by favoring the re-emergence of viruses which had almost disappeared,
but above all that we have proposed treatments which promote mutations making them more dangerous for the general population. We would like to remove the human species from the surface of the globe that we could hardly do better.
@xabitron1 @lisa_iannattone @mildanalyst @MeetJess @RadCentrism @C_A_Gustave @CorneliusRoemer @firefoxx66 @FLAHAULT @shay_fleishon @RajlabN @JosetteSchoenma @ArisKatzourakis
@ejustin46 @xabitron1 @lisa_iannattone @mildanalyst @MeetJess @RadCentrism @C_A_Gustave @CorneliusRoemer @firefoxx66 @FLAHAULT @shay_fleishon @RajlabN @JosetteSchoenma @ArisKatzourakis There is one major difference between anti-Spike mAbs and small molecule antivirals causing lethal mutagenesis (such as molnupiravir and favipiravir) : mAbs only mutate Spike, the others mutate the entire genome, including the one of human cells…
@dfocosi @xabitron1 @lisa_iannattone @mildanalyst @MeetJess @RadCentrism @C_A_Gustave @CorneliusRoemer @firefoxx66 @FLAHAULT @shay_fleishon @RajlabN @JosetteSchoenma @ArisKatzourakis Thanks for you comment.