Bio Balance, Inc. @bio1balance
The philosophy of Bio Balance is that accurate descriptions of drug-receptor interactions will lead to the development of better drugs. #biotech #pharmacology bio-balance.com New York, NY Joined October 2015-
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Ligand efficacy modulates conformational dynamics of the µ-opioid receptor - nature.com/articles/s4158…
Cysteine residues in signal transduction and its relevance in pancreatic beta cells - frontiersin.org/journals/endoc…
"Bio Balance" AND receptor - google.com/search?sca_esv…
"The Origins of Life's Sensoria" youtu.be/rMh0-y54DoI?si… via @YouTube
Very excited to share our new preprint where we develop MIC, a deep metric learning tool for classifying waters & ions in experimental structures; fantastic collaboration with the extremely talented Laura Shub and Selina Liu from the Keiser lab! biorxiv.org/content/10.110…
Revolutionizing Medicinal Chemistry: The Application of Artificial Intelligence (AI) in Early Drug Discovery - mdpi.com/1424-8247/16/9… #science #research #chemistry #biology #physics #mathematics #biophysics #pharmacology #AI
How we treat: "net shift" AND "electrostatic switch" AND "receptor activation" - google.com/search?q=%22ne… #science #research #chemistry #biology #physics #mathematics #biophysics #pharmacology
The fourth of four videos explaining the physical underpinnings for the net shift theory of pharmacology - youtube.com/watch?v=_2p4gr… #science #research #chemistry #biology #physics #mathematics #biophysics #pharmacology
The third of four videos explaining the physical underpinnings for the net shift theory of pharmacology - youtube.com/watch?v=O6fKMb… #science #research #chemistry #biology #physics #mathematics #biophysics #pharmacology
The second of four videos explaining the physical underpinnings for the net shift theory of pharmacology - youtube.com/watch?v=WE_leJ… #science #research #physics #mathematics #biophysics #pharmacology
The first of four videos explaining the physical underpinnings for the net shift theory of pharmacology - youtube.com/watch?v=Rt4Q6i… #science #research #physics #mathematics #biophysics #pharmacology
My complete pharmacologic theory for receptor dynamics is in this book. google.com/search?q=%22Or… #science #pharmacology #biophysics #biochemistry #research
ChatDOC is here: chatdoc.com/chatdoc/#/shar… #ScienceResearch #Science #biotech #research #technology #TechNews #AI
The net shift model produces the full range of all possible pharmacodynamics of the receptor response. - google.com/search?sca_esv… #pharmacology #physiology #science #biology #biophysics #chemistry #research
These are the four videos that describe our research that is summarized in this book: amazon.com/Origins-Lifes-… The videos beginning at the bottom are in an ascending order to watch successively. -Enjoy! youtube.com/watch?v=_2p4gr…
Understanding Fundamental Equilibrium Concepts
A new video series exploring the mysteries of receptors, senses, perception and consciousness. youtube.com/watch?v=Rt4Q6i… #receptors #senses #perception #consciousness #science #YouTube #video
Electrostatic AND "Net Shift" AND receptor - google.com/search?q=Elect… #science #pharmacology
Jiafei Mao @Jiafei_Mao
1K Followers 3K Following Embracing scientific complexity & cultural diversity. Exploring #membraneprotein #GPCR using 🧲#NMR #DNPNMR and partner techniques 🚣🏊🧘♂️💪🥘🍷🐈DrGPCR @DrGPCR
4K Followers 5K Following Join the movement, connect, share, and speed GPCR drug discovery. #GPCR Ecosystem. https://t.co/jPzcdANDn1Wojciech (Wojtek) Kop.. @wojciechkopec3
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63 Followers 254 Following Slightly obsessed with GPCRs | Sometimes when I pipette, I weep | 無言フォロー失礼しますAI in the Life Scienc.. @AILSCI
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4K Followers 5K Following Join the movement, connect, share, and speed GPCR drug discovery. #GPCR Ecosystem. https://t.co/jPzcdANDn1Wojciech (Wojtek) Kop.. @wojciechkopec3
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"The Origins of Life's Sensoria" youtu.be/rMh0-y54DoI?si… via @YouTube
Very excited to share our new preprint where we develop MIC, a deep metric learning tool for classifying waters & ions in experimental structures; fantastic collaboration with the extremely talented Laura Shub and Selina Liu from the Keiser lab! biorxiv.org/content/10.110…
Had re-read this really great piece by Oriah Mountain Dreamer: genius.com/Oriah-mountain… Decided to try the same format to express ideas from the perspective of the Diverse Intelligence framework that colleagues and I have been working on: thoughtforms.life/some-free-vers…
Do plants develop cancer? Since trees live long and have many cells, shuld we expect to see "tumoral forests" as the on in the image (my drawing)? Spoiler: negative answers to both questions (with exceptions). Understanding why is a fascinating story @ara_anderson @AguadeGuim
How we treat: "net shift" AND "electrostatic switch" AND "receptor activation" - google.com/search?q=%22ne… #science #research #chemistry #biology #physics #mathematics #biophysics #pharmacology
My complete pharmacologic theory for receptor dynamics is in this book. google.com/search?q=%22Or… #science #pharmacology #biophysics #biochemistry #research
The net shift model produces the full range of all possible pharmacodynamics of the receptor response. - google.com/search?sca_esv… #pharmacology #physiology #science #biology #biophysics #chemistry #research
#compchem Good read: On the Validity of Constant pH Simulations doi.org/10.1021/acs.jc…
The sheer scale of the proteome is forbidding. New ideas and technologies are scaling up to the enormity of the proteome. The biology vistas will be spectacular. blog.slavovlab.net/2023/11/29/pro…
Check out our latest publication that explores how membrane mimetics and their composition can affect GPCR energy landscapes. A huge thank you to @thakurnaveen7, our collaborators and @MatthewEddyLab for continued support and guidance. sciencedirect.com/science/articl…
Always good to remember that #SARSCoV2 , similar to all other six human coronaviruses known, reaches the brain through the olfactory epithelium by invading peripheral nerve terminals and propagating via axonal transport towards the olfactory cortex, where it spreads to other…
Four largely ignored coronaviruses circulate in humans without causing great harm and may portend the future for #SARSCoV2. Learn more in this @NewsfromScience feature: scim.ag/5ZD
On our morning walk, my dad unleashed his new theory of aging. He says it's a floating point rounding error in the cosmic simulation calculating our physiological state changes.
Delighted to share our study on probing the conformational diversity in GPCR-beta-arrestin complexes !!! A genetically-encoded nanobody sensor reveals conformational diversity in beta-arrestins orchestrated by distinct seven transmembrane receptors biorxiv.org/content/10.110…
These are the four videos that describe our research that is summarized in this book: amazon.com/Origins-Lifes-… The videos beginning at the bottom are in an ascending order to watch successively. -Enjoy! youtube.com/watch?v=_2p4gr…
Understanding Fundamental Equilibrium Concepts
A new video series exploring the mysteries of receptors, senses, perception and consciousness. youtube.com/watch?v=Rt4Q6i… #receptors #senses #perception #consciousness #science #YouTube #video
Electrostatic AND "Net Shift" AND receptor - google.com/search?q=Elect… #science #pharmacology
Available today: the final journal version of FoldingDiffusion in @NatureComms Led by former intern @Kevin_E_Wu with @alexijielu @vdbergrianne @SarahAlamdari @james_y_zou and @avapamini
We present Folding Diffusion: a diffusion model for protein structure inspired by physical protein folding. Let by @Kevin_E_Wu during his internship, with @alexijielu @vdbergrianne @james_y_zou @avapamini Code: github.com/microsoft/fold… Preprint: arxiv.org/abs/2209.15611