Murphy Lab @_Murphy_Lab
Structural and mechanistic study of proteins, especially redox- and metalloproteins biophys.mpg.de/redox-metallop… Frankfurt, Germany Joined September 2021-
Tweets49
-
Followers456
-
Following87
-
Likes18
Happy to share that our work on the FDX2-bound core ISC complex is now published in @NatureComms 🎉 nature.com/articles/s4146… By the way, we are now also on @bluesky! 🦋 bsky.app/profile/bjmurp…
🎉 Our latest preprint is now online 👉 biorxiv.org/content/10.110… Congrats to @RalfSteinhilper who determined #cryoEM structures of the ferredoxin 2-bound core iron-sulfur cluster assembly complex under reducing and turnover conditions at 2 Å resolution. More below! 👇 🧵 1/8
1
13
92
9K
5
Our elemental mapping work, combining cryo-EM and EELS to REEL analysis, is now also published on Nature Methods: nature.com/articles/s4159… For a highlight “reel”, see here 👇
Happy to announce that our efforts to establish elemental mapping for cryo-EM ❄️ by EELS 🌈 are now shared on bioRxiv: biorxiv.org/content/10.110… Congratulations to @zoliviapg and co-authors! But wait - Can we map elements in 3D? 🧵👇 1/6
Congrats to @MaxYin_211013 and co-authors! Big thanks to X-ray team: Tristan Wagner, Olivier Lemaire and Mélissa Belhamri @MarineMicrobio; computational team: Gerhard Hummer and José Guadalupe Rosas Jiménez @HummerLab; MS team: Anna Shevchenko @mpicbg for the great collaboration!
The story doesn’t end there. QM/MM calculations reveal novel features of the catalytic metalloclusters, the C-cluster and A-cluster. The results suggest an electron storage mechanism for the C-cluster, and the configuration of the A-cluster in the ligand-free resting stage.
How could CO₂ fixation occur in anaerobic and ancient life? Our new preprint sheds light on catalytic mechanism of the key enzyme CODH/ACS in the Wood-Ljungdahl pathway. Watch the summary movie to see how CO₂ is transformed into acetyl-CoA. Read more: t.ly/u3Ir0
Happy to see our study on the structure of 46-kDa Streptococcus pneumoniae NOX out in @NatureSMB! Congratulations to the authors @PABLOSANSEGUND3 and @vicsnorr 🥳 Check it out here (open-access) 👉 t.ly/T0oej
Excited to share our preprint: “Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase” in which we obtained a structure of a 46-kDa membrane protein to 2.2 Å resolution without fiducials. tinyurl.com/zycuw3p6
Many thanks to our colleagues @MPIbp and collaborators in the group of Roland Lill @Uni_MR for cooperation on this story and a study of the sulfur transfer intermediates in the frataxin-bound core ISC complex: doi.org/10.21203/rs.3.… 🧵 8/8
Our study clarifies how FDX2 binds to the core ISC complex and confirms that de novo FeS biosynthesis is a highly concerted process. This might have implications for understanding the concentration-dependent effects of frataxin in diseases like Friedreich’s ataxia. 🧵 7/8
🎉 Our latest preprint is now online 👉 biorxiv.org/content/10.110… Congrats to @RalfSteinhilper who determined #cryoEM structures of the ferredoxin 2-bound core iron-sulfur cluster assembly complex under reducing and turnover conditions at 2 Å resolution. More below! 👇 🧵 1/8
More research will be needed to reach single-atom sensitivity. In the meantime, we’d be grateful for any feedback and hope you enjoy the read! Also, if you’d like to join the team: We do have an open post-doc position! ^^ recruitingapp-5577.de.umantis.com/Vacancies/299/… 🧵 6/6
A big thanks for their contributions, especially to @_Higor_Rosa, as well as Dietmar Riedel, @YuSebyChen, @FilipPetegem, and the always-helpful team from CEOS whose awesome CEFID we have been relying on, as well as @DECTRIS_News whose ELA has been crucial to this project. 🧵 5/6
Happy to announce that our efforts to establish elemental mapping for cryo-EM ❄️ by EELS 🌈 are now shared on bioRxiv: biorxiv.org/content/10.110… Congratulations to @zoliviapg and co-authors! But wait - Can we map elements in 3D? 🧵👇 1/6
Max Planck Institute ... @MPIbp
6K Followers 418 Following Our research concerns biological membranes with particular emphasis on the structure and function of membrane proteins. #Biophysics #cryoEM #structuralbiology
Misha Kudryashev 🔬... @MishaKudryashev
5K Followers 845 Following Group Leader at the Max Delbruck Center for Molecular Medicine @MDC_Berlin Professor at Charité in Berlin Immigrant Science / Biophysics / Cryo-EM
Beck Laboratory @Beck_Laboratory
3K Followers 484 Following #MolecularSociology @MPIbp @becklab.bsky.social
The Wilfling Lab @WilflingLab
580 Followers 763 Following Investigating mechanisms of eukaryotic cellular quality control @MPIbp via #cryoET, #cellbiology and #massspectrometry
Ieva Drulyte @IevaDrulyte
2K Followers 947 Following Structural biologist | PhD @AstburyCentre 🇬🇧 | #CryoEM | She/her
Inga Hänelt @IHanelt
582 Followers 191 Following Scientist interested in all kind of membrane transport processes
Yongchan Lee @YongChan_zzz
982 Followers 394 Following Interested in cryo-EM of transporters. All views are my own.
Sonja Welsch @sonjawelsch
785 Followers 520 Following Head of #ElectronMicroscopy Facility @MPIbp. Yay for #cryoem and #cryoET, but frozen is not always better. #teamtomo, #virology & personal views.
Ben Engel @bengeliscious
7K Followers 3K Following https://t.co/fKnd53tQsT @biozentrum. Plants and algae in a changing climate. ❄🔬 OF 🌿 4THE 🌍! I’m not here anymore. Find me on bsky🦋 @cellarchlab.com
Gatsogiannis Lab @GatsogiannisLab
618 Followers 424 Following Gatsogiannis Lab SoN, IMPB, Münster. CryoEM of complex nanosystems. https://t.co/WX3NFobNgI
Kelvin Lau 🧬🧪�... @klausenhauser
3K Followers 3K Following 🇨🇦🇭🇰 @EPFL_en protein production + structure facility 🇨🇭| ex @ubc @uwaterloo @unige_en | #proteins #plants #transit #cats #politics | My views + ☁️ 🪡 🐘
Patricia Rodriguez Ma... @_PatriRM
990 Followers 319 Following Lecturer (Asst Prof) in Inorganic Chemistry at the University of Leicester | #BioinorgChem | #PhysicalChem | #Echem | #IRspectroscopy
Rebecca Thompson @Bex_16
3K Followers 2K Following All things #CryoEM #ElectronMicroscopy #VolumeEM @thermosciEMSpec She/her. Opinions definitely my own.
Javier @Javi_Lizaendo
330 Followers 421 Following Post-doc at @WilflingLab @MPIbp Previously @EMBL @KingsCollegeLon Membrane-protein interactions / Structural Biology Hiking He/Him/His
Israel Fernandez @IsraelF96135088
4K Followers 1K Following Nonconformity is the necessary condition for self-realization.
James A. Letts @LettsScience
1K Followers 680 Following Assistant Professor of Molecular and Cellular Biology, UC Davis. Membrane protein biochemistry, biophysics and structural biology #cryoEM. Bioenergetics.
Alexander Harms @AHarms485
9K Followers 5K Following Bacteriophages, dormant bacteria, and bacterial immunity. Assistant Professor of Molecular Phage Biology at ETH Zurich.
Sazanov Lab @SazanovL
1K Followers 399 Following Professor, Institute of Science and Technology Austria. Structure/function of molecular machines and membrane proteins, cryoEM. Fellow of Royal Society
IntegralTechnosapienH... @IntegralTe53568
17 Followers 910 Following Integral Technosapien Humanism is the prevailing will of humanity. There's so many causes one could fight for, but if you align with this one you will win.
Ati @AtiRafiei
4 Followers 84 Following Graduate student department of Biophysics University of Toronto. interested in enzymology, drug discovery and structural biology.
Zhang Lab @xiaofengzh11027
0 Followers 77 Following
Max Planck Society @maxplanckpress
180K Followers 2K Following Official account of the Max Planck Society. Devoted to basic research in #physics #astronomy #chemistry #biology #mathematics #socialsciences & the #humanities
CryoAI Nanomega @CryoAI_Nanomega
17 Followers 13 Following CryoEM × AI | Structural biology CRO Serving pharma, research institutes & AI for Science innovators.
Aditi Moharana 242100... @Aditi210006
2 Followers 53 Following
Shekhar @Shekhar68617309
0 Followers 14 Following
Namita Menon @namitamenon123
25 Followers 290 Following Interested in protein biochemistry and structural biology
Shay @Shay7219
0 Followers 450 Following
Oleksii Zdorevskyi @olZdorevskyi
13 Followers 33 Following
Aggregate @AggregateOA
2K Followers 4K Following A multidisciplinary journal dedicated to publishing cutting-edge aggregate research (Impact Factor = 13.7, CiteScore = 18.3)
The Quantum Ufo @theQuantumUfo
189 Followers 2K Following In search of UFOs engines. The other side from @sergioperezf the Nuclear Quantum Gravity ☢️ https://t.co/o4sQd5ngLn
Peter Kirchweger @PeterKirchweger
54 Followers 475 Following PostDoc in the Elbaumlab at @WeizmannScience
Angewandte Chemie @angew_chem
114K Followers 3K Following Angewandte Chemie, a journal of the German Chemical Society (GDCh, @GDCh_aktuell) - a leading journal in #chemistry published by @WileyGlobal in @Weinheim
Ribbe Hu Labs @HuRibbe
289 Followers 390 Following Metalloprotein assembly and catalysis; bioinorganic chemistry; structural biology; spectroscopy; microbiology
ql h @qll124_
0 Followers 258 Following
Yogendra Kumar @ChYogendrapatel
12 Followers 38 Following I have earned PhD in molecular dynamics simulation of soft material from the department of chemical engineering at Indian Institute of Technology Madras.
Jessica Soares @jessicacsfla
198 Followers 369 Following Metalloproteins, EPR and redox chemistry. Postdoc at Boston University.
Structure @Structure_CP
7K Followers 995 Following Structure is a monthly publication of @CellPressNews dedicated to research at the cutting edge of #structuralbiology. Tweets are by the Editors.
Tanmay Pandey @tanmay1902
85 Followers 608 Following 5th Yr BSMS @IiserMohali. Biophysics. Cells, and Synthetic Biology. MS Thesis @IiserMohali and @MPIbp . || ॐ नमः शिवाय ||
Debendra Kumar @Debendra_12
50 Followers 962 Following Research Scholar at CSIR-IGIB|| Computational Structural Biology Lab|| Autophagy|| Protein Structure
Aniket Rana @AniketR28
34 Followers 331 Following Structural Biology enthusiast. Science 🧪🧫🧬🦠. IISER Mohali - 2025 | Biology Major
Odelia @Theighs0Avcns
5 Followers 404 Following If you don't know me, what qualifications do you have to give me advice? If you don't know me, why do you talk to me?
Znger @Znger4
510 Followers 6K Following Dream works believer. mAbs,CAR T, 😊NIK in NFkB pathway-G-proteins-,Chl Binding Proteins, DmNucleobindin-Microb Diversity-Reduviids
Dr. Geo (Michel Geova... @GeoSantiagoM
6K Followers 5K Following Asst. Prof. @UConnMCB @UConn 🔬🧬🏳️🌈 (He/él) Mexican, Indigenous, 1st gen #methane #microbiology #microbiome #astrobiology @ArchaeaBio @ArchaeaPowerHr
Pedro Queiroz @JPedroFQueiroz
79 Followers 210 Following Doctoral researcher at Max Planck Institute for Terrestrial Microbiology. Interested in the biosynthesis of the Fe-hydrogenase cofactor. 🇧🇷 living in 🇩🇪
Will Bowles @WillBowles7
84 Followers 317 Following Cryo-ET focused PhD student at University of Oxford, Diamond Light Source and Rosalind Franklin Institute
KiraKira77✨ @_KiraKira77_
0 Followers 41 Following
Thilo Duve @ThiloDuve
1 Followers 39 Following
sofia.defelice @sofia_defelice
54 Followers 159 Following PhD student with a strong passion for structural biology
Himanshu Sharma @shrma_h
341 Followers 912 Following Group leader@NOVA-FCT. Parasites, viruses and cryoEM.
Ekaterina Poliukhina @EPoliukhina
6 Followers 58 Following PhD student in Materials Science and Engineering, SuNMIL, EPFL Specialist's degree in Colloid Science, Lomonosov MSU
Ashleigh Kropp @Ashleigh_Kropp
194 Followers 293 Following PhD student in the Grinter Lab @MonashUni researching how bacteria extract energy from air
Chinmay Sen @ChinmaySen5
193 Followers 1K Following Structural Biologist | Researcher @StJude | Alumnus @kuacbdOfficial, @WesternUPharm
Patryk Kalinowski �... @KalinowskiSTEM
95 Followers 1K Following ChemBio PhD Candidate @BUChemistry ‘24 - ‘?? | Fulbright Scholar @UChicagoBMB ‘22 - ‘24 #3ProcentNaNauke #FirstGen
Bhattacharyya Lab @moitrayee_lab
1K Followers 1K Following science enthusiasts in Pharmacology @Yale studying molecular mechanisms of cell signaling in cancer and neurodegeneration (https://t.co/hKUrRJr3D2)
@ @DustinMorado
617 Followers 982 Following
Black In Biophysics @BlackInBiophys
3K Followers 2K Following Recognizing and celebrating Black scientists in Biophysics | Founder: @StevensSostre | Logo: @TG_PhD | Web: https://t.co/TrI8mL1ylR | #BIBPSWeek2021 link 👇🏾
Jack Bravo @jpkbravo
1K Followers 688 Following Assistant Professor at IST Austria | Studying nucleoprotein complexes one particle at a time
Nick Stein @maxx_healthspan
804 Followers 7K Following evidence based medicine for a long and healthy life - maximizing healthspan and longevity - building a medical service
Paul V Thomas @paul_v_thomas
243 Followers 1K Following
Valeria Kalienkova �... @VKalienkova
339 Followers 471 Following Ukie, postdoc at UiB, P. Kursula lab. https://t.co/PfBtzB7ykz, [email protected]
CryoGourmet Fan @hongcheng_fan
459 Followers 1K Following cryo-em, single particle, tomo, sample preparation，deeplearning
Misha Kudryashev 🔬... @MishaKudryashev
5K Followers 845 Following Group Leader at the Max Delbruck Center for Molecular Medicine @MDC_Berlin Professor at Charité in Berlin Immigrant Science / Biophysics / Cryo-EM
cryoEM Papers @cryoEM_Papers
12K Followers 0 Following I'm a bot that surveys the cryoEM literature for you! Operated by @fredericpoitev1 & @CorneliusGati, adapted from PaperBots twitter app developed by @fxcoudert
Beck Laboratory @Beck_Laboratory
3K Followers 484 Following #MolecularSociology @MPIbp @becklab.bsky.social
Structura Biotechnolo... @structurabio
6K Followers 402 Following Algorithms, Software and Systems for Cryo-EM. Makers of CryoSPARC.
Sjors Scheres @SjorsScheres
15K Followers 1 Following This account is no longer in use. Follow our science on: https://t.co/mlxULCj9zl
Arne Moeller @MoellerGroup
1K Followers 951 Following Full Professor, University of Osnabrück, Dept of Structural Biology
Inga Hänelt @IHanelt
582 Followers 191 Following Scientist interested in all kind of membrane transport processes
Yongchan Lee @YongChan_zzz
982 Followers 394 Following Interested in cryo-EM of transporters. All views are my own.
Sonja Welsch @sonjawelsch
785 Followers 520 Following Head of #ElectronMicroscopy Facility @MPIbp. Yay for #cryoem and #cryoET, but frozen is not always better. #teamtomo, #virology & personal views.
Ben Engel @bengeliscious
7K Followers 3K Following https://t.co/fKnd53tQsT @biozentrum. Plants and algae in a changing climate. ❄🔬 OF 🌿 4THE 🌍! I’m not here anymore. Find me on bsky🦋 @cellarchlab.com
Rebecca Thompson @Bex_16
3K Followers 2K Following All things #CryoEM #ElectronMicroscopy #VolumeEM @thermosciEMSpec She/her. Opinions definitely my own.
EMBL @embl
67K Followers 910 Following The European Molecular Biology Laboratory drives visionary basic research and technology development in the life sciences. 🦋 https://t.co/r840DbdMXO
Wim Hagen @WimJHH
4K Followers 539 Following Cryo-EM. Playing drums with the world-famous Janse Bagge Bend.
Patrick Cramer @mpgpresident
13K Followers 565 Following President of the Max Planck Society since 2023 – dedicated to advancing science for the benefit of society. | @maxplanckpress
Lukas Stelzl @l_stelzl
1K Followers 1K Following Disordered proteins, nucleic acids and their dynamics complexes & condensates. Integrating simulations and experiments.
Poul Nissen🇩🇰�... @PoulNissen
3K Followers 1K Following Vice-dean for research @AarhusUni @NatSci_AU. Structural neurobiology professor. Opinions are my own - on science and politics in Danish&English.
Ariane Briegel @BriegelAriane
4K Followers 936 Following Professor, Leader of the Integrative Structural Cell Biology Unit at Institut Pasteur @[email protected]
Max Yin @MaxYin_211013
10 Followers 59 Following Postdoc @MPIbp @_Murphy_Lab, dad, history buff, trail lover; Passion for #cryoEM, #StructuralBiology, redox proteins
Higor Rosa @HVDRosa
272 Followers 479 Following Structural Biology | Currently Pre-Doc (PhD student) @SimoneMattei19 Lab (@EMBL) I Former @_Murphy_Lab (@MPIbp) | BSc./MSc. @charles_garratt Lab (@usponline)
Filip Van Petegem @FilipPetegem
463 Followers 133 Following Scientist studying bio-electricity, muscle excitation-contraction coupling and cardiac arrhythmias. University of British Columbia, Life Sciences Institute.
EMBO YIP @EMBO_YIP
4K Followers 892 Following News and discussion for EMBO Young Investigators and Installation Grantees. Expect tweets about EMBO activities, publications, awards, collaborations etc.
Victor Dubach @vicsnorr
76 Followers 266 Following PhD student @_Murphy_Lab @MPIbp with @imprs_cbp Interested in #cryoEM 🔬❄️, redox and membrane proteins
Bjorn Forsberg @bforsb
598 Followers 347 Following Associate Professor in structural bioinformatics at Linköping University, improving methods in and around cryo-EM
Theresa Gewering @thgeweri
70 Followers 85 Following
Thomas Meier @ThomasMeierLab
168 Followers 84 Following Dad, scientist, teacher. Director Liechtenstein-Institute. Former Chair in Structural Biology.
Thorsten Wagner @pixelbaumarkt
654 Followers 183 Following Project group leader @mpimoph (@intein Lab). 🐘 [email protected]
Sarah Piper @SarahJ_Piper
2K Followers 1K Following Postdoctoral Researcher @MIPS_DDB @MonashUni in Melbourne. Interested in #cryoEM ❄🔬 #SciVis🔎💡🎨 Views and Arts are my own. Founder of @PiperProteins She/her
PNCC @CryoEM_PNCC
2K Followers 1K Following Our mission is to provide free services to a diverse group of researchers and train the next generation of cryo-electron microscopy users.
Vivek Sharma @vivekvivsharma
1K Followers 2K Following PI of Computational Bioenergetics Group. Associate Professor, University of Helsinki. Studies mitochondrial proteins with multiscale computational methods.
James Birrell @JamesBirrell86
406 Followers 177 Following
Elizabeth Wright @erwright73
4K Followers 4K Following Cryo-EM Investigator and Professor at the University of Wisconsin - Madison | Cryo-EM, cryo-ET, CLEM | enveloped viruses, eukaryotic cells, prokaryotes & phages
Melanie McDowell @Mel_McDowell22
359 Followers 286 Following Group Leader @MPIbp exploring ER membrane protein biogenesis
Sharon Grayer Wolf @ShaLGW
2K Followers 483 Following @WeizmannScience cryoEM junkie, with particular enthusiasm for cellular tomography of all kinds, cellular ultrastructure and in-situ chemical characterization
Constanze Pinske @CoPinni
94 Followers 108 Following Former German microbiology scientist: interested in anaerobic metabolism, mother, gardener and now high school chemistry teacher. She/Her
IMPRS on Cellular Bio... @imprs_cbp
892 Followers 174 Following Joint PhD Program of @MPIbp @goetheuni @uni_mainz @fias_science aiming to gain a complete molecular-level understanding of the cell.
SEMC @SEMC_NYSBC
688 Followers 125 Following The Simons Electron Microscopy Center provides expertise and resources for understanding both molecular and cellular structures. https://t.co/2i55qQBkYO
CCP-EM @ccp_em
3K Followers 87 Following Collaborative Computational Project for Electron cryo-Microscopy https://t.co/w9OXHhB5fh
Jensen Lab @theJensenLab
4K Followers 774 Following This is the official Twitter feed of the Jensen Lab @BYU
Sachse Group @SachseGroup
1K Followers 336 Following The Sachse group @fz_juelich: #cryoEM #cryoET #CLEM #FIBSEM #autophagy. Account curated by members of the group. Retweet ≠ endorsement.
Alex J Noble @alexjamesnoble
2K Followers 406 Following Husband=) Founder, CryoArcana | CryoEM/ET/FIB-SEM Specialist | Topaz co-creator | Advisor | https://t.co/XfPhzR7zDr
Pablo San Segundo @PABLOSANSEGUND3
266 Followers 763 Following Postdoc at @CNIOStopCancer. Before at @ProteoFun ISCIII and @_Murphy_Lab at MPI_Biophysics. Interested in Protein Biochemistry, Proteomics and CryoEM 🌈🦕🦎❄️🦠
Hauke Hillen @hauke_hillen
2K Followers 773 Following Professor @yourUMG @uniGoettingen, Group Leader @mpi_nat ; Structural biology of gene expression. https://t.co/9fwC20BvzU
Natalie Bärland @BarlandNatalie
187 Followers 484 Following
Dr. Yonca Ural-Blimke @YoncaUB
347 Followers 866 Following Biochemist | AltAc, Alumni @MPIbp @EMBL @uni_tue | Mother of two | #SciComm #WissKomm #WomenInSTEM #FCKNZS | she/her 🇪🇺🏳️🌈
Sriram Subramaniam @cryoem_UBC
2K Followers 19 Following CEO, @Gandeeva_Tx Therapeutics and Gobind Khorana Canada Excellence Research Chair @UBC, applying #cryoEM to develop better therapeutics for cancer
Ali Punjani @a_punjani
1K Followers 50 Following CEO of Structura Biotechnology Inc, makers of cryoSPARC software for single-particle cryo-EM analysis. PhD student studying ML/AI in Toronto.
Olivia Pfeil-Gardiner @zoliviapg
110 Followers 101 Following PhD student @_Murphy_Lab * Imaging with electrons!
MPI for Brain Researc... @MpiBrain
6K Followers 380 Following The Max Planck Institute for Brain Research is one of the world-leading institutions studying the neural circuits in the brain. Tweets by MPI Brain PR office.
Matteo Allegretti @MatteoAll
891 Followers 959 Following Cellular structural biology (cryo-EM/ET, biophysics) | nature, society | Group Leader at @MRC_LMB and father, prev. @MPIbp @embl | https://t.co/4fxzFaTL8W
Özkan Yildiz @Oezkan_YildizZ
146 Followers 277 Following
Cristina Paulino @CPaulino_
4K Followers 1K Following Full Prof @uniHeidelberg 🇩🇪, before 🇳🇱🇨🇭, from🇵🇹| Passion for #MembraneProteins, #cryoEM, #StructuralBiology, #Biochemistry. https://t.co/v1ONsjSrQg
Wolf Lab @HiCryoEM
3K Followers 4K Following Cryo-EM on Okinawa! Structural Biology. Biophysics. Virology. Microbiology. OIST. Opinions are my own. 🇦🇹🇪🇺🇺🇸🇯🇵🇮🇱🇹🇼🇪🇸🇱🇰🇧🇷🇻🇪🇺🇦🇲🇽
Henning Stahlberg @LabStahlberg
3K Followers 370 Following Cryo-EM, Parkinson‘s Disease, Membrane Protein Structure and Function, and Method Development
mike strauss @EM_mikestrauss
680 Followers 178 Following Father to my children, husband of an angel, professor of the biophysical, drinker of the coffee - Non Impediti Ratione CogitationisYou might like
Dmitry Shvarev
@DmitryShvarev
344 Followers