Wayland Cheng Lab @WChengLab
Biophysical and structural studies of ligand-gated ion channels. Lipid modulation. @WUSTL_AnesRsrch Washington University Department of Anesthesiology wchenglab.org Washington University Joined August 2020-
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A postdoc position is available in our lab to study how ion channels communicate with one another. Cryo-EM, electrophysiology, protein biophysics. A great opportunity for structural biologists to learn electrophysiology methods or vice versa. vanpetegemlab.com/opportunities.…
Celebrating another year of successful collaboration with the @WChengLab at the Dandelion. Looking forward to seeing you in LA for #BPS2025!
These simulations of membrane proteins in nanodiscs were so fun. Thank you @WChengLab for your continued enthusiasm for simulations that go beyond the basics - we are lucky computational collaborators! @VikramDalal_37 @PageAnesthesia
These simulations of membrane proteins in nanodiscs were so fun. Thank you @WChengLab for your continued enthusiasm for simulations that go beyond the basics - we are lucky computational collaborators! @VikramDalal_37 @PageAnesthesia
It's my pleasure to share that I have been awarded an AHA postdoctoral fellowship. I would like to acknowledge my mentor @WChengLab for unimaginable support, referres: @Pravindrak_IITR, @ShaillyTomar and Alex Evers, and @American_Heart for belief in my proposal. @WChengLab
This is a very interesting paper showing that nanodiscs, typically used to preserve lipids for structural analysis of membrane proteins, can affect the structure of the target protein. First paper I read this year, happy 2024! nature.com/articles/s4146…
🥁Presenting a #namd protocol for SAFEP, the surprisingly straight-forward approach to FEP. Easy to follow tutorial? ✅ Extensive troubleshooting guide? ✅ This project with @jerome_henin 's groups was years in the making! Now at @livecomsj tinyurl.com/yezhr73h
It’ll be great to have a new postdoc in my group to lead a new project (biochem/biophys/ephys). If there’s anyone out there who wants to chat, message me. I might be a little weird, but the proteins we’re interested in are weirder!
📢Please RT📢 CIMED is looking to recruit a new tenure-track faculty member doing cryo-EM analyses of membrane proteins. For new or established faculty, and departmental affiliation in Anesthesiology, Biochemistry or Cell Biology, this is a fantastic opportunity! @WUSTL
We’re hiring! Projects combine genomics, in vivo ephys and synaptic physiology to understand how plasticity in basal ganglia circuits give rise to maladaptive decision making- with a focus on models of substance use disorder and chronic pain! (1/n)
Announcing FAER’s approved Spring 2023 Grantees! Join us in congratulating these outstanding physician-investigators & read more on our website! asahq.org/faer/about/new… #Anesthesiology #Research #TheFutureIsFAER #FAERgrantees #FAERgrants @AndreaJIbarra
3 postdocs landing dream jobs, 1 PhD student graduating means: A)I'm so proud of these amazing scientists and happy for their success & B) We have opportunities to recruit new colleagues!
Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1 dlvr.it/Sk1M8M
We are looking for a new postdoc to join our group. There are several MS-based research opportunities in our group, including membrane proteins, viral proteins, and amyloid-forming proteins. If interested, please see the link below wustl.wd1.myworkdayjobs.com/External/job/C…
Please check out new work from my lab, published this week in @NatureComms. Great collaborative work with my @NIGMS K08 mentor @CrinaNimigean and my anesthesiologist/biophysicist buddy @WChengLab. rdcu.be/c6lKa
Forgot to mention at the end of my talk that I’m looking for grad students/postdocs/res scientists curious about how the pacemaker rate adapts. If you are interested let me know!!!
Interesting structural insights into phospholipid control of TREK1 gating! Grateful to @PRiegelhaupt for the opportunity to contribute native MS measurements. @iHeart_proteins @CrinaNimigean
Interesting structural insights into phospholipid control of TREK1 gating! Grateful to @PRiegelhaupt for the opportunity to contribute native MS measurements. @iHeart_proteins @CrinaNimigean
If you missed @VikramDalal_37's poster yesterday, come see a poster by Mark Arcario @PageAnesthesia (B303) on nanodisc effects on pLGIC structure. doi.org/10.1101/2022.1…
If you missed @VikramDalal_37's poster yesterday, come see a poster by Mark Arcario @PageAnesthesia (B303) on nanodisc effects on pLGIC structure. doi.org/10.1101/2022.1…
For those going to @BiophysicalSoc #BPS2023, come check out @EzrySantiago's talk at the Membrane Transport Subgroup Saturday, 2:35 pm! Ezry is presenting on the Absolute Binding Affinities of Phospholipids to ELIC by Streamlined Alchemical FEP (SAFEP): biophysics.org/2023meeting/pr…
For those going to @BiophysicalSoc #BPS2023, I will be presenting some results on using simulation to probe the effects of nanodiscs on ion channel structure. Stop by and say “Hi!” Poster B303, 1:45-2:45pm.
WashU Anesthesiology .. @WUSTL_AnesRsrch
936 Followers 327 Following Research Divisions for @WashUanesthesia. At the forefront of innovative, cutting edge knowledge in both lab-based & clinical research.
Maria Falzone @MariaFalzone9
282 Followers 410 Following 🧪🧬 postdoc in the MacKinnon lab, interested lipid regulation of membrane proteins 🔬
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accardilab @accardilab
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Claire @ClaireZhao323
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Society of General Ph.. @sgpweb
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Kristian Frandsen @Kr.. @KrFrandsen
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Takeshi Irie @oncoanesthesia
114 Followers 436 Following questing to improve care at the interface of cancer and anesthesia
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Sophion Bioscience A/.. @sophionbio
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Ciara Wallis @ciara__wallis
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SensoryNeuropharmacol.. @SensoryNeuroph1
545 Followers 630 Following Venoms, toxins, ion channels and pain. Lab Twitter of Irina Vetter
Willow Coyote-Maestas @willowcoyote
2K Followers 1K Following Assistant Professor at @UCSF_BTS | @HHMINEWS HGF | He/Him| mixed (Jicarilla Apache descent, Xicano, white) scientist | Loving membrane proteins every day
Gourav choudhir @gouravchoudhir
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Ardem Patapoutian @ardemp
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cryoEM Papers @cryoEM_Papers
13K Followers 0 Following I'm a bot that surveys the cryoEM literature for you! Operated by @fredericpoitev1 & @CorneliusGati, adapted from PaperBots twitter app developed by @fxcoudert
WashU Anesthesiology .. @WUSTL_AnesRsrch
936 Followers 327 Following Research Divisions for @WashUanesthesia. At the forefront of innovative, cutting edge knowledge in both lab-based & clinical research.
Maria Falzone @MariaFalzone9
282 Followers 410 Following 🧪🧬 postdoc in the MacKinnon lab, interested lipid regulation of membrane proteins 🔬
Osama Harraz @OsamaHarraz
3K Followers 5K Following Assistant Professor - Attempting to decode the complexity of vascular physiology and blood flow control, one ion channel at a time. @Harraz_Lab @UVMvermont
Tibor Rohacs @RohacsTibor
2K Followers 1K Following Scientist working on TRP and Piezo ion channels, trying to understand their roles in health and disease.
Wojciech (Wojtek) Kop.. @wojciechkopec3
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Dr. Theanne Griffith .. @doctheagrif
7K Followers 1K Following Asst. Prof @UCDavis 👩🏾🔬Somatosensation | Electrophysiology, Award-winning Children’s Book Author 📚 @netflixfamily @randomhousekids @abramskids she/her
Rob Gereau @robgereau
3K Followers 1K Following Neuroscientist studying chronic pain. Vice Chair for Research at @WUSTL_AnesRsrch and Director of @WashUPain Center. Cofounder of @NeuroLuxInc
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Zhaozhu Qiu @ZhaozhuQ
1K Followers 410 Following Associate Professor of Physiology & Neuroscience at Johns Hopkins University studying ion channels and brain disease.
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2K Followers 1K Following Pursuing science with a social conscience. Grateful for life's twists. Wasn't supposed to be me. Embracing the journey with gratitude and solidarity 🌍✨
accardilab @accardilab
2K Followers 755 Following We study structure and function of ion channels, transporters and scramblases. #Biophysicists #Biochemists #Addictedtocoffee
Ute Hellmich @HellmichGroup
2K Followers 512 Following Biochemistry/Structural Bio @UniJena IOMC & @microverse_exc; (membrane) protein dynamics admirer, parasite aficionado and coffee addict. @hellmichgroup.bsky.soc
Dan Minor @ElectrosomeUCSF
1K Followers 140 Following Biophysicist | UCSF Professor | Traveller | Chef @[email protected]
PlessLab @LabPless
2K Followers 482 Following ion channels, biophysics, chemical biology, protein engineering and molecular neuroscience; Professor at University of Copenhagen
Scheuring Lab @ScheuringLab
2K Followers 999 Following We perform atomic force #microscopy (#AFM) of biological samples with a particular interest in #membrane #channels and #transporters / opinions: Simon Scheuring
JGenPhysiol @JGenPhysiol
3K Followers 786 Following The Journal of General Physiology publishes peer-reviewed research in physiological problems at the cellular and molecular level. Est. 1918 - @RockUPress
Ben Garcia @GarciaLabMS
15K Followers 678 Following Professor and Head of @WUSM_BMB. Studying protein PTMs in chromatin biology. #TeamMassSpec cheerleader. Working towards changing academia. Views my own 🇺🇸🇲🇽
Yining Jiang @YiningJiang
139 Followers 252 Following Biophysics PhD student with @ScheuringLab WeillCornell/Cornell University. Boston University, 2018. BNDS 北京十一学校, 2014. 📍NYC
Claire @ClaireZhao323
159 Followers 769 Following Anesthesia resident👩🏻⚕️| Focus on #Translational #Pain research targeting #ionchannels 💊| Mice watcher🔬 | Looking for a PhD position! | 🌈 🏊🏻
BK @KCNMA1
22 Followers 45 Following Gene encoding the BK channel. Proud of my introns and exons. Pronouns: BK, Slo1, MaxiK
Shumaila Iqbal Siddiq.. @Shumaila_iq
79 Followers 634 Following Postdoctoral research fellow, School of Medicine, Johns Hopkins University, Baltimore Maryland
SMALP Network @smalpnet
389 Followers 299 Following Community interested in native nanodiscs, lipid recognition, membrane proteins & models. Join us at the SMALP WebConference on June 18, 2024 - Michael Overduin
Paul Kerby @kjab3
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ASoranno @AndreaSoranno
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George @Geo_Eid_
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251 Followers 448 Following Basketball enthusiast, foodie and assistant professor
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Contrexin Lab @UC Dav.. @DrContrexin_Lab
127 Followers 203 Following Exploring cellular black holes. This account dedicates to our lab's scientific endeavors @ucdavishealth. PI's @DrContrexin account is now reserved for venting
Sophion Bioscience A/.. @sophionbio
717 Followers 458 Following #AutomatedPatchClamp - Pioneering #IonChannels #PatchClamp #planarpatch #ephys #electrophysiology #QPatch #Qube #QPatchCompact
Ciara Wallis @ciara__wallis
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Arun K. Shukla @arshukla
10K Followers 132 Following Professor and Sonu Agrawal Memorial Chair, IIT Kanpur
Marta Filizola @martafilizola
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SensoryNeuropharmacol.. @SensoryNeuroph1
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Daniel Mihaylov @danielmihaylov7
23 Followers 136 Following
Trends in Biochemical.. @TrendsBiochem
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Kato @oxkawaka
5K Followers 734 Following 構造生物学、元結晶屋で今は電顕屋。クライオ電子顕微鏡で難しい標的を解くのが専門/ A researcher tackling cryo-EM structures of challenging proteins
Wohlever_Lab @WohleverL
1K Followers 2K Following We are a cellular biochemistry lab at the University of Pittsburgh. Interests include mitochondria, membrane proteostasis, cancer, & neurodegeneration.
Ali Kusay @a_kusay
119 Followers 170 Following
Mehdi @MehdiSahihi
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André Nadler @nadlerlab
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Makayla Freitas @mak_freitas
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Parthiban Marimuthu, .. @DrPMarimuthu
296 Followers 851 Following Multiscale simulations • Membrane proteins • GPCRs • Transporters • Ion channels @AboAkademi
Tobias Raisch @TobiasRaisch
248 Followers 161 Following Biochemist and structural biologist | Project group leader @mpimoph | Passionate about cycling, punk rock & politics | He/him | Views are my own
Rosa HP Sca @ro_sca26
416 Followers 2K Following Postdoc'ing @WUSTLcellbio 👩🏻🔬 Rare musculoskeletal diseases & ion channels 🔬 Bookworm and avocaddicted 📍🇺🇸 | 🇮🇹
Avner Schlessinger @SchlessingerLab
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Raúl Padrón @raulpadron
1K Followers 5K Following Curiosity-driven research rules! Muscle Structural Biologist, Professor. UMass Chan Medical School, Division of Cell Biology and Imaging, Padrón-Craig Lab.
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158 Followers 228 Following Structural Biologist. Cryo-EM, HS-AFM, MD simulations, X-ray crystallography, membrane proteins. Postdoc @ScheuringLab
Nandan Haloi, PhD @nandan_haloi
782 Followers 944 Following Computational Biophysicist. MSCA postdoc fellow with @eriklindahl, KTH, in collaborations with @JanssenBelgium. PhD @emadtaj, TCBG, UIUC.
WUSTL ENDURE @WUSTL_ENDURE
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Colin Nichols Lab @ColinNicholsLab
337 Followers 805 Following Focused on molecular mechanisms of channel activity and roles of ion channels in diseases. Part of Cantu syndrome interest group @WUSTL @WUSTLcellbio
Jay Lu, PhD @jayjay_lu
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Harraz Lab @Harraz_Lab
156 Followers 220 Following Research in the Harraz Lab, located in beautiful Vermont and led by @OsamaHarraz, is focused on vascular ion channels and signal transduction pathways.
Juan Felipe Beltrán,.. @offbyjuan
692 Followers 3K Following I'm just an Alien, standing in front of a country, asking it to let me improve their biotechnology {Algorithms, Protein Sequencing, Drug Discovery, HCI, jokes}
Tom Vondriska @VondriskaLab
3K Followers 2K Following Chromatin, heart disease, and other stuff https://t.co/FXPeNnTnfU
Meagan Belcher Dufris.. @meagandufrisne
631 Followers 2K Following Postdoc in the #ColumbusLab at UVA studying membrane proteins. Alum of the #ManciaLab at Columbia. Avid knitter. I also like funny people! (she/her)
PauloCTSouza @SouzaPauloCT
1K Followers 782 Following Martini developer, Researcher at ENS-CNRS in Lyon, consultant, trying to make CG models more useful for molecular design and drug/vaccine delivery 🖥️+🍸=💊💉
Cheryl Stucky @Dr_CherylStucky
2K Followers 381 Following I'm a neuroscientist at the @MedicalCollege and study #pain and touch #neuroscience
Candie Paulsen Lab @LabPaulsen
262 Followers 451 Following @CandieDandie's biochemistry research group @YaleMBB consisting of unique individuals united in our use of diverse approaches to study pain signaling.
Carlo Camilloni @CarloCamilloni
3K Followers 2K Following Associate Professor @LaStatale Theoretical biophysicist and computational structural biologist. dev @plumed_org @PlumedN
Chris Toseland @ChrisToseland
4K Followers 3K Following Prof. Cancer Biophysics @ShefUni_ClinMed Investigating #Myosin, Nuclear Organisation and #Mechanobiology #microscopy #singlemolecule #superresolution
Robert White, MD MS @RobertWhiteMD
703 Followers 577 Following @WCMAnesthesia | OB | Population Health Sciences Researcher | 🇺🇸| RT 🚫endorsement | tweets my own and do not represent my employer or any funding sources
Willow Coyote-Maestas @willowcoyote
2K Followers 1K Following Assistant Professor at @UCSF_BTS | @HHMINEWS HGF | He/Him| mixed (Jicarilla Apache descent, Xicano, white) scientist | Loving membrane proteins every day
Chow @ChowHanChua
371 Followers 331 Following Lecturer at The University of Sydney 🇦🇺 | Ion channels. VGICs. LGICs. Leak channels.
Excited to share our new paper : "Novel anti-inflammatory effects of the IL-1 receptor in kidney myeloid cells following ischemic AKI" frontiersin.org/articles/10.33… @Duke_Anesthesia @DukeKidney @aces_duke @XiaohanLu_Duke @Yanting17931824 @htn_StevenC @RLWBowman @DukeOPSD @Duke_PCB
🤩🤩🤩 our work made it to the @NatureSMB cover. And then for such a great issue 🤩🤩 thanks to @VKalienkova @TimLynagh and Mowgli 🥳🥳 check @KatCiazynska comments 👇🏼
in case you all like membrane proteins, there's a lot of cool stuff in the fresh-off the press @NatureSMB issue nature.com/nsmb/volumes/3…
Thrilled to announce our latest work in @NatureSMB on HS-AFM single-molecule structural biology with @ScheuringLab ! Marching towards our long-standing goal, we've directly linked the conformations of a single molecule to its instantaneous activity... nature.com/articles/s4159…
Just returned from a fabulous visit at @WUSTL. Big thanks for the many interactions and in particular @ChandaLab06 for hosting! (special treat to be sharing the table with two VCF heroes of my PhD days, Baron and Yongchang)
HS-AFM single-molecule structural biology uncovers basis of transporter wanderlust kinetics - now out @NatureSMB - free link rdcu.be/dE0wf @YiningJiang @BoudkerLab @MBiophys_WCMSKI @WCMResearch @WCMAnesthesia Conformational landscape of a single molecule
Read about the next chapter in our fruitful collaboration with @ScheuringLab! New HS-AFM developments help visualize the conformational landscapes of individual glutamate transporters, leading to many cool insights about their mechanism. Congrats to @YiningJiang and all authors!
HS-AFM single-molecule structural biology uncovers basis of transporter wanderlust kinetics - now out @NatureSMB - free link rdcu.be/dE0wf @YiningJiang @BoudkerLab @MBiophys_WCMSKI @WCMResearch @WCMAnesthesia Conformational landscape of a single molecule
Check out our new paper quantifying tension activation of mechanosensitive K2P channels by pressure + ultrasound co-led by @MBenSorum and @DocterTrevor! Lots of new data to see since the preprint last year including a comparison of TRAAK, TREK1, and TREK2 nature.com/articles/s4146…
Take a look at our new preprint on the molecular architecture of synaptic vesicles purified from mouse brains and in neurons grown on grids biorxiv.org/content/10.110… 🧵👇
Happy to share our new paper on the structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930. Collaboration between V. Chubanov, A. Sobolevsky @AlexanderSobol6 and M. Kurnikova @MKCMU labs. @knadezhdinPhD @arthurCantab cell.com/cell-reports/f…
Congratulations to Anna Annanchenko and @RuiyanGao for their @CommsBio paper: State-dependent binding of cholesterol and an anionic lipid to the muscle-type Torpedo nicotinic acetylcholine receptor (nature.com/articles/s4200…).
Delighted to share first paper from our lab on GLIC published in @NatureComms. Great efforts by all authors @nikydna, @zhuowenli1997, David, @Asha_ManikkothB. Thanks to our collaborator @philbiggin. The article can be found at nature.com/articles/s4146…
Excited to share our latest collaboration with the @CorryLab and Zhang Lab, this time on OSCA/TMEM63 channels out today in @Nature @VictorChangInst nature.com/articles/s4158…
Ecstatic to report the NOA for our new Co-PI R01 with @JABLab3 ! So excited to embark on this pioneering collaborative work in Cystic Fibrosis! Thanks to collaborators @ColinNicholsLab & Mark Miller! @WUSTLmed @WUSTLPCCM @BBSBwustl @WashUDPS
Nice press release about my talk today at ACS Spring 2024 on our work on ERRs. I am so grateful to my wonderful team who made this possible.
Bahaa Elgendy understands that some people might be too busy, or lazy, to exercise. So, his team is looking to mimic the benefits of exercise through a pill instead. This could also help people facing muscle loss due to disease or aging. #ACSSpring2024 brnw.ch/21wHZ2q
Congratulations to our newest Anesthesiology Residency Class! We are thrilled to welcome this extraordinary group of physicians to #WashUanesthesia and @WUSTLmed! 🎉 👏 🎉 Learn more at anesthesiology.wustl.edu/match-day-2024…
I'm deeply honored and grateful to receive the 2024 Young Investigator Award by the @CancerRF. This funding will boost our research on ion channels in the context of tumor immunotherapy.
This grant is intended to solve a catch-22 facing many young scientists: not having enough data to solicit funding for large-scale studies, and yet not having enough funding to collect further data. Join us in congratulating these eight individuals.
THEY SAID WE COULDN'T DO IT........well, no one actually said that. But in our updated manuscript with @CasperGoverde, @GoldbachNico, and @befcorreia we show you can now design soluble analogues of membrane proteins with preserved functional features! biorxiv.org/content/10.110…
Big congratulations to @AndreaSoranno and @RuiZhangWUSTL for being promoted to Associate Professor with Tenure in @WUSM_BMB. Highly deserved and we are excited about what the future holds for you both! We are all honored to be your colleagues.
Check out our latest work by @MattGabrielleRU on BioRxiv, where we identified endogenous lipid modulators that selectively inhibit Piezo2 channels over Piezo1 and modulate mechanosensitivity in mice. biorxiv.org/content/10.110…
She did it! I would like to introduce Dr. SenthilKumar!! @gogo_gopss @LabFreed 🥂
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